Vitamin supplementation and blood pressure in Type 2 diabetes (Sep. 2012)
ABSTRACT:
Vitamin supplementation may stabilize systolic blood pressure in adults with Type 2 diabetes across seasons.
Methods:
•Dietary intake, vitamin supplementation, blood pressure, and anthropometric parameters were assessed each season for 1 year (174 adults with Type 2 diabetes).
•Separate linear regression models were constructed for high and low sun exposure periods to examine associations of systolic blood pressure with dietary vitamin D intake and vitamin supplement use (adjusted for age, gender, BMI, ethnicity, smoking, alcohol, physical activity, antihypertensive medication and nutrient intake).
•Robustness of findings was confirmed with within–subject repeated measures analysis, including an interaction term for sun exposure period.
Results:
•Vitamin D intake from food sources was low year–round and no conclusive association with blood pressure was identified during either period.
•Systolic blood pressure was 5.1 mmHg lower during the low sun exposure period (95% CI 0.5–9.7) in daily supplement users compared with non–users.
•The interaction term between supplement use and sun exposure period was significant (low sun exposure* no supplement, P = 0.02).
•Systolic blood pressure was relatively stable in users (low and high sun exposure periods, respectively, mean ± SE: 135.2 ± 2.6 mmHg and 134.2 ± 2.5 mmHg), but not in non–users (140.2 ± 2.7 mmHg and 130.5 ± 2.5 mmHg).
Reference:
http://www.mdlinx.com/nursing/news-article.cfm/4221483/703/diabetes-mellitus--type-2





